portant note: Medicine is an ever-changing science
undergoing continual development. Research and
clinical experience are continually expanding our
knowledge, in particular our knowledge of proper
treatment and drug therapy. Insofar as this book
mentions any dosage or application, readers may rest
assured that the authors, editors, and publishers have
made every effort to ensure that such references are in
accordance with the state of knowledge at the time
of production of the book.
Nevertheless, this does not involve, imply, or express
any guarantee or responsibility on the part of the
publishers in respect to any dosage instructions and
forms of applications stated in the book. Every user is
requested to examine carefully the manufacturers’
leaflets accompanying each drug and to check, if
necessary in consultation with a physician or specialist,
whether the dosage schedules mentioned therein or
the contraindications stated by the manufacturers
differ from the statements made in the present book.
Such examination is particularly important with drugs
that are either rarely used or have been newly released
in the market. Every dosage schedule or every form of
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Some of the product names, patents, and registered
designs referred to in this book are in fact registered
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