This Special Issue, “Non-Coding RNAs and Extracellular Vesicles in Cancer Crosstalk: Diagnostic and Therapeutic Implications”, presents a collection of cutting-edge research articles and reviews that explore the critical roles of non-coding RNAs (ncRNAs) and extracellular vesicles (EVs) in cancer biology. The contributions highlight their diagnostic and therapeutic potential, with particular emphasis on lung and liver cancers.
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Notable reviews examine the involvement of ncRNAs in airway diseases and their emerging role as liquid biopsy biomarkers for lung cancer. This issue also investigates the role of EV-derived microRNAs (EV-miRNAs) in cancer progression and explores the theranostic potential of Piwi-RNAs contained within extracellular vesicles. Altogether, this collection underscores the promise of ncRNAs and EVs as innovative biomarkers and therapeutic targets, offering a comprehensive overview of recent advances and emphasizing the significance of the ncRNA–EV axis in cancer diagnosis and treatment.