The new edition of this book highlights the recent advances and state-of-the art in surgical and non-surgical management of thyroid cancer. Readers will learn about the latest advances and recommendations in the field, from molecular studies and biomarkers to the changing epidemiology, kinase inhibition in drug discovery and new surgical approaches, such as intra-operative neural monitoring and robotics. The management of differentiated thyroid cancer as well as childhood cancer, survivorship and clinical trial design and findings and how these fit into cancer management are discussed in detail.
This comprehensive volume provides an overview of the current world literature and outlines the practical aspects of management from world leaders in this field and helps clinicians and patients on practical matters. With a selection of authors from around the world it draws on international experience giving a global perspective to the topic. Following on from the success of the firstedition, it uses a multidisciplinary, evidence-based approach centered on the patient, discussing guidelines and how these have improved the quality of care and outcomes.
This guide is aimed mainly at thyroidologists of all disciplines, (in training or experts) students, non-specialist clinicians, nursing staff, all the disciplines involved in a multidisciplinary team such as surgeons – Head & Neck or Endocrine and General Surgeons, Oncologists, Endocrinologists, Nuclear Medicine Physicians, Nuclear Medicine Physicists, Radiologists, Pathologists, Specialist Nurses, Geneticists, Clinical Psychologists, Palliative Care Physicians and, of course, patients.
Table of contents (34 chapters)
Front Matter
Pages i-xv
Radioiodine and external radiation therapy
An Overview of the Management of Thyroid Cancer
Ernest L. Mazzaferri
Pages 1-28
The UK Multidisciplinary Approach to Management of Thyroid Cancer
Front Matter
Pages 29-29
The UK Evidence-Based Guidelines for the Management of Thyroid Cancer: Key Recommendations
Pat Kendall-Taylor
Pages 31-38
Thyroid Cancer Multidisciplinary Team and the Organizational Paradigm
Ujjal K. Mallick
Pages 39-53
Thyroid Cancer from the Perspective of a Patient
Jennifer S. Pitman
Pages 55-58
The Role of the Specialist Nurse
Caroline Owen-Hafiz
Pages 59-63
The Role of the Clinical Psychologist
Katherine Kendell
Pages 65-71
The Diagnosis of Thyroid Cancer
Front Matter
Pages 73-73
Thyroid Nodules
Petros Perros
Pages 75-81
Thyroid Cancer and the General Practitioner
Geoffrey Mitchell, Duncan Leith
Pages 83-93
The Role of the Pathologist
Anne Marie McNicol
Pages 95-107
Thyroid Cancer and the Endocrinologist
Wilmar M. Wiersinga
Pages 109-117
Initial Thyroid Surgery
Front Matter
Pages 119-119
Download chapter PDF
The Specialist Endocrine Surgeon
Nadine R. Caron, Cord Sturgeon, Orlo H. Clark
Pages 121-134
Initial Thyroid Surgery for Patient with Differentiated Thyroid Carcinoma
Douglas B. Villaret, Ernest L. Mazzaferri
Pages 135-147
Management of Cervical Lymph Nodes in Differentiated Thyroid Cancer
John C. Watkinson
Pages 149-163
Complications of Thyroid Surgery
Thomas W.J. Lennard
Pages 165-168
Non-surgical Management of Differentiated Thyroid Cancer
Front Matter
Pages 169-169
Non-surgical Management of Thyroid Cancer
Masud S. Haq, Clive Harmer
Pages 171-191
Non-surgical Management of Differentiated Thyroid Cancer
Fertility Following Treatment with Iodine-131 for Thyroid Cancer
Louiza Vini
Pages 193-197
Follow-up Management of Differentiated Thyroid Cancer
Front Matter
Pages 199-199
Recombinant Human TSH (rhTSH): Use in Papillary and Follicular Thyroid Cancer
Furio Pacini, Martin J. Schlumberger
Pages 201-210
Thyroglobulin
Carole A. Spencer, Shireen Fatemi
Pages 211-228
Follow-up of Patients with Differentiated Thyroid Carcinoma
Martin J. Schlumberger, Sophie M. Leboulleux, Furio Pacini
Pages 229-236
Management of Differentiated Thyroid Carcinoma Patients with Negative Whole-Body Radioiodine Scans and Elevated Serum Thyroglobulin Levels
Ernest L. Mazzaferri
Pages 237-251
Medullary Thyroid Carcinoma
Front Matter
Pages 253-253
Medullary Thyroid Cancer: Diagnosis and Management
Aldo Pinchera, Rossella Elisei
Pages 255-279
Nonmedullary Thyroid Cancer and the Role of the Geneticist
Sanjay Popat, Richard S. Houlston
Pages 281-299
Thyroid Cancer in Children
Front Matter
Pages 301-301
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Thyroid Cancer in Childhood
Nicholas J. Sarlis, Wellington Hung
Pages 303-320
Radiation-Induced Thyroid Cancer: Lessons from Chernobyl
James A. Fagin, Yuri E. Nikiforov
Pages 321-326
The Use of Stable Potassium Iodide (KI) in the Event of a Nuclear Emergency
Christoph Reiners
Pages 327-331
Diagnostic Imaging Studies for Thyroid Cancer
Front Matter
Pages 333-333
Ultrasound of the Thyroid
David L. Richardson
Pages 335-340
Diagnostic Nuclear Medicine Investigations in the Management of Thyroid Cancer
Susan E.M. Clarke
Pages 341-357
CT and MRI in Thyroid Cancer
Julian E. Kabala
Pages 359-368
Papillary Microcarcinoma
Front Matter
Pages 369-369
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Papillary Microcarcinoma of the Thyroid
William D. Drucker, Richard J. Robbins
Pages 371-389
Aggressive Thyroid Cancers
Front Matter
Pages 391-391
Aggressive Thyroid Cancers
Rare Thyroid Cancers
Masud S. Haq, Clive Harmer
Pages 393-402
Management of Anaplastic Thyroid Cancer
Jan Tennvall, Göran Lundell, Göran Wallin
Pages 403-409
Specialist Palliative Care for Anaplastic Thyroid Carcinoma
Mary Comiskey
Pages 411-419
Future Developments and Directions for Research in Thyroid Cancer
Front Matter
Pages 421-421
Emerging Therapies for Thyroid Cancer
Matthew D. Ringel
Pages 423-428
Clinical Trials for Thyroid Carcinoma: Past, Present, and Future
Steven I. Sherman
Pages 429-434
Back Matter
Pages 435-445